Retinoblastoma
Conditions
Brief summary
This study evaluate the effect of dexmedetomidine on intelligence test in pediatric patients with multiple anesthesia exposure. Children who are diagnosed with retinoblastoma and receive first exam under general anesthesia before age of 2 are included. Intelligence test will performed when patients' age are 4.
Interventions
DRUGDexmedetomidine
Dexmedetomidine (1 mcg/kg loading for 10 min, then 1 mcg/kg/min continuous infusion) is used with sevoflurane in every time of general anesthesia
Sponsors
Seoul National University Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
No minimum to 2 Years
Healthy volunteers
No
Inclusion criteria
* Patients who are first diagnosed as retinoblastoma and scheduled for EUA and treatment under general anesthesia before age of 2
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| IQ score at age of 4 | year 4 | Korean-Wechsler Preschool and Primary Scale of Intelligence test (score \>131, high; score 116-130, high-normal; socre 85-115, normal; score 70-84; low-normal; score \<69; low) |
| Developmental Test | year 4 | visual-Motor Integration test |
Countries
South Korea
Contacts
Primary ContactJi-Hyun Lee, MD, PhD
Backup ContactJi-Hyun Lee
Outcome results
None listed