Cross-sectional Study of Anorectal Function and Quality of Life in Patients With Middle and Low Rectal Cancer

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04697303

Enrollment

600

Registered

2021-01-06

Start date

2020-10-26

Completion date

2021-03-28

Last updated

2021-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rectal Cancer

Brief summary

Understanding the quality of life and anorectal function changes in patients with middle and low rectal cancer after surgery can guide patients to recover after surgery and provide a valuable reference for surgeons in the selection of surgical methods. The purpose of this study is to: (1) Investigate the complication rate, recurrence and metastasis rate and survival of patients with middle and low rectal cancer. (2) QLQ-C30 and QLQ-CR29 questionnaires were used to assess the quality of life of patients with low- and middle-level rectal cancer at different periods after surgery. (3) Wexner constipation score and LARS syndrome score for anorectal function after operation for low rectal cancer. (4) The CIPE ejaculatory function score, IIEF-5 International Erectile Function Score, and FSFI-6 Female Sexual Function Index were used to assess the changes in sexual function of patients with low- and middle-position rectal cancer after surgery.

Interventions

OTHERanorectal function test

anorectal function test

Study design

Observational model

OTHER

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

1. Postoperative patients with middle rectal cancer 2. Postoperative patients with low rectal cancer

Exclusion criteria

(1)Patients refused to participate

Design outcomes

Primary

Measure	Time frame	Description
Overall survival	five years after the operation	defined as time from the date of sugery to death

Secondary

Measure	Time frame	Description
QLQ-CR29	Every three months after the operation	the score of Quality of life questionnaire QLQ-C29
Wexner	Every three months after the operation	the score of questionnaire Wexner
LARS	Every three months after the operation	the score of questionnaire LARS
QLQ-C30	Every three months after the operation	the score of Quality of life questionnaire QLQ-C30
CIPE	Every three months after the operation	the score of questionnaire CIPE
FSFI-6	Every three months after the operation	the score of questionnaire FSFI-6
IIEF-5	Every three months after the operation	the score of questionnaire IIEF-5

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026