Left Atrial Appendage Velocity, Left Atrial Function, Left Atrial Structure
Conditions
Brief summary
Radiofrequency ablation of atrial fibrillation combined with left atrial appendage closure can not only improve symptoms in patients with non-valvular atrial fibrillation, but also prevent left atrial appendage thrombosis. The safety and effectiveness of left atrial appendage occlusion have been confirmed by randomized controlled trials and actual experience. Among patients with different left atrial appendage emptying speeds, there are limited studies on the structure and function of the left atrial appendage after LAA closure. In this study, patients with persistent nonvalvular atrial fibrillation were selected for radiofrequency ablation combined with LAA closure. The sinus rhythm was restored after the operation. According to the different emptying speed of the left atrial appendage, they were divided into a high-flow rate group and a low-flow rate group. The differences in the structure and function of the left atrium between the two groups were analyzed.
Interventions
Patients with nonvalvular atrial fibrillation underwent radiofrequency ablation combined with left atrial appendage closure and recovered to sinus rhythm after the operation. To study the changes of left atrial organization and function of two groups of patients with different left atrial appendage emptying speeds.
Sponsors
The Second Hospital of Hebei Medical University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients who received atrial fibrillation radiofrequency ablation combined with left atrial appendage closure. Exclude Criteria * Patients with incomplete data. * Device embolism. * Residual shunt around the device found by transesophageal echocardiography greater than 5 mm. * Mitral valve stenosis. * Artificial valve. * Atrial septal defect. * Dilated cardiomyopathy * Moderate Severe mitral regurgitation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in the structure of the left atrium | 1year | Measure the left atrial transverse diameter, anteroposterior diameter, upper and lower diameter. |
| Changes in the function of the left atrium | 1year | Left atrium volume. Two-chamber and four-chamber left atrium strain and strain rate, left atrium storage function, channel function and pump function. |
Countries
China
Outcome results
None listed