Infertility
Conditions
Brief summary
The purpose of this study is to determine if embryo culture under a single CO2 setting improves blastocyst formation rate.
Detailed description
Following enrollment, patients will undergo ovarian stimulation and oocyte retrieval per routine as previously consented to at the clinic. IVF stimulation protocol will be at the discretion of the patient's individual provider, per routine. Intracytoplasmic Sperm Injection (ICSI) will be performed and embryos will be cultured to the blastocyst stage per routine. There are no changes to the embryology care itself, the only difference within the study is the CO2 level within the incubator pending the patient's randomization.
Interventions
OTHERContinuous CO2 Level
Embryos will be cultured in a single, continuous CO2 setting
Sponsors
Reproductive Medicine Associates of New Jersey
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
Major Inclusion Criteria for participants: 1\. Patients undergoing IVF stimulation cycle with plan for subsequent FET Major
Exclusion criteria
for participants: 1. All patients who do not voluntarily give their written consent for participation 2. Male partner with \<100,000 total motile spermatozoa per ejaculate (donor sperm is acceptable) 3. Use of surgical procedures to obtain sperm
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| blastulation rate | approximately one week | the number of zygotes that reach the blastocyst stage |
Countries
United States
Outcome results
None listed