Donor Site Complication, Muscle; Ischemic
Conditions
Keywords
Elastography; Donor site morbidity
Brief summary
In the field of reconstructive microsurgery, donor site morbidity after free flap harvest is one of the key factors to consider when choosing among different options of free flap. Peroneal artery-based free flap, such as fibula flap or peroneal flap, is one of the popular options of free flap. There are a plenty of literature using a variety of modalities to evaluate the donor site morbidity after free fibula harvest, such as gait analysis. Elastography has been used to evaluate the stiffness change of soft tissue, such as skeletal muscle, or liver. The purpose of this study is to use elastography to evaluate the stiffness of lower leg muscle after peroneal artery-based free flap harvest.
Detailed description
A total of twenty-three patients will be recruited at National Taiwan University Hospital Yunlin Branch. All of them will receive fibula flap or peroneal flap harvest operations. At the time points of pre-operation, 1-month post-operation, 3-month post-operation, and 6-month post-operation, the muscles of both legs of each patient will be evaluated by elastography, and the function of both legs will be evaluated by American Orthopedic Foot and Ankle Score (AOFAS). Paired t-test will be used to compare the results of each evaluations.
Interventions
DEVICEElastography
Use elastography to evaluate the stiffness of lower leg muscle after peroneal artery-based free flap harvested
Sponsors
National Taiwan University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* No previous major operations over both legs * Able to walk freely during daily life * Going to receive peroneal artery-based free flap harvested from one leg
Exclusion criteria
* Previous major operations over either leg * Unable to walk freely during daily life
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Lower Leg Muscle stiffness | 6 months | Lower leg muscle stiffness after peroneal artery-based flap harvested; Name of measurement: elastic modulus; Unit: kPa |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| American Orthopedic Foot and Ankle (AOFAS) scale | 6 months | AOFAS scale change after peroneal artery-based flap harvested, highest score:100, lowest score: 0; A higher score means a better outcome |
Countries
Taiwan
Outcome results
None listed