CCTA Improves Clinical Management of Stable Chest Pain

Conditions

Coronary Artery Disease, Coronary Computed Tomography Angiography, Invasive Coronary Angiography, Major Adverse Cardiovascular Events, Optimal Medical Therapy, Revascularization, Stable Chest Pain

Brief summary

The investigator aims to prospectively enroll patients who were referred for coronary computed tomography angiography (CCTA) for the assessment of stable chest pain (SCP) suspected of obstructive coronary artery disease (CAD). All patients underwent CCTA according to established guidelines and local institutional protocols. The imaging data were evaluated using different image post-processing software to comprehensively analyse anatomical, functional and histological information of coronary. This study will determine if CCTA-based imaging evaluation can provide more informaton to improve clinical management for SCP, including fewer MACE and better decision-making of downstream investigations and therapeutic interventions.

Yahang Tan, Chang Liu, Tao Chen, Yina Li, Chengjian Wang et al. (7 authors)

Reviews in Cardiovascular Medicine2024-03-04

10.31083/j.rcm2503085

Association between Coronary Artery Disease Reporting and Data System–recommended Post–Coronary CT Angiography Management and Clinical Outcomes in Patients with Stable Chest Pain from a Chinese Registry

Jia Zhou, Chunjie Li, Hong Zhang, Chang Liu, Junjie Yang et al. (23 authors)

Radiology2023-06-0112 citations

10.1148/radiol.222965

Validation and Comparison of PROMISE and CONFIRM Model to Predict High-Risk Coronary Artery Disease in Symptomatic and Diabetes Mellitus Patients

Hantao Jiang, Jinping Feng, Chao Feng, Pei Ren, Kai Ren et al. (7 authors)

Reviews in Cardiovascular Medicine2022-03-013 citations

10.31083/j.rcm2303080

Interventions

DIAGNOSTIC_TESTCCTA

All patients underwent CCTA according to established guidelines and local institutional protocols. The imaging data were evaluated using different image post-processing software to comprehensively analyse anatomical, functional and histological information of coronary.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

* symptomatic patients with SCP suspected of obstructive CAD. * referred for CCTA for the assessment of SCP. * ≥18 years of age. * signed informed consent.

Exclusion criteria

* acute coronary syndromes * previous CAD or coronary revascularization * nonsinus rhythm * cardiomyopathy, valvular disease, congenital heart disease or left cardiac insufficiency because of other reasons

Design outcomes

Primary

Measure	Time frame	Description
Major adverse cardiovascular events	10 years	Cardiac death and myocardial infarction

Secondary

Measure	Time frame	Description
Medication prescription	10 years	Change for medication prescription of antiplatelet agents, anti-ischemic drugs, lipid-lowering agents, angiotensin-converting enzyme inhibition and so on, attributed to CCTA results or unplanned,
Coronary revascularization	10 years	PTCA, PCI or CABG occurred at follow-up after CCTA, attributed to CCTA results or unplanned.
Number of Participants with Death	10 years	—
Invasive coronary angiography	10 years	Invasive coronary angiography occurred at follow-up after CCTA, attributed to CCTA results or unplanned.
Number of Participants with Cardiac death	10 years	—
Number of Participants with Myocardial infarction	10 years	—
Number of Participants with Stroke	3 years	—

Countries

China

Contacts

Primary ContactJia Zhou

zhoujiawenzhang@126.com+8615522485560

Outcome results

None listed