Cross-sectional Examination of the Reliability of Oral Implants

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04690621

Acronym

PeriX2012

Enrollment

192

Registered

2020-12-30

Start date

2012-07-01

Completion date

2013-08-07

Last updated

2020-12-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periimplantitis

Keywords

peri-implant disease prevalence incidence tolerance titanium

Brief summary

Aim of the multi centrical, cross-sectional study is the registration of the prevalence and incidence of mucositis and periimplantitis.

Detailed description

Aim of the multi centrical, cross-sectional study is the registration of the prevalence and incidence of mucositis and periimplantitis. Additional clinical examination of the tolerance of titanium using cytosine analysis of periimplant sulcus smear and of blood lymphocytes on titanium plates in vitro. In total 10 centers will examine clinical, genetic and microbiological parameters in 200 patients during 12 months. Study hypothesis: The incidence of mucositis and periimplantitis during a time period of 10 years in patients is less than 30%

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Patients with oral implants inserted after 01.04.2002 * Periodical recall

Exclusion criteria

* No other titanium implants inside the body

Design outcomes

Primary

Measure	Time frame	Description
IL-1ß	6 month	Interleucin 1 beta in peripheral blood

Secondary

Measure	Time frame	Description
MMP-8	6 month	Metallomatrixproteinase-8 in Periodontal Sulcus Fluid
BOP	6 months	Bleeding on probing
PD	6 months	Probing Depth

Countries

Germany

Outcome results