Organ Transplantation
Conditions
Brief summary
This study aims to constitute a collection of biological materials from in transplant patients and to provide biological materials from transplanted patients in order : i) validate new theory on the cause of allograft loss, ii) develop innovative biomarker for rejection and other transplantation-related conditions (such as BK virus nephropathy, Post-transplant lymphoproliferative disorder ( PTLD) ...)
Interventions
OTHERBiobank
For each patient included in the study the following samples will be collected at the indicated time points after transplantation: * Serum samples and plasma sample: Day1, Month 1, Month 3, Month 6, Month 12, month 60, month 120 and at the time of each allograft biopsy. * Urines samples: Month 3 and Month 12 and at the time of each allograft biopsy. * Peripheral Blood Mononuclear Cell (PBMC): for each organ allograft biopsy. * Allograft biopsies: systematically at Month 3, and Month 12, and for cause in case of allograft dysfunction.
Sponsors
Hospices Civils de Lyon
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Male or Female patient ≥18 years old * Recipient of an organ transplant * Written informed consent
Exclusion criteria
* Non-affiliation to a social security system. * Subjects deprived of liberties * Pregnant or breastfeeding woman
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the biological samples | At inclusion | The goal of this study is to provide biological materials from transplanted patients |
| Change Biological Samples | Month 1 | The goal of this study is to provide biological materials from transplanted patients |
Countries
France
Contacts
Primary ContactOlivier Thaunat, MD
Backup ContactEmmanuel Morelon, MD
Outcome results
None listed