Vitamin D Levels and Postoperative Pain in Laparoscopic Cholecystectomy

Effect of Vitamin D Levels on Postoperative Pain and Narcotic Analgesia in Patients With Laparoscopic Cholecystectomy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04687527

Enrollment

Registered

2020-12-29

Start date

2020-05-15

Completion date

2021-04-30

Last updated

2021-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain, Vitamin D Deficiency

Keywords

laparoscopic cholecystectomy, Vitamin D Deficiency, Postoperative Pain

Brief summary

The deficiency of vitamin D is common in patients with gastrointestinal system disorders. Vitamin D has been associated with chronic non-specific musculoskeletal pain and migraines due to anti-inflammatory effects. This prospective observational study will undergo elective laparoscopic cholecystectomy surgery between 18 and 65 years, is planned to participate in ASA (American Society of Anesthesiologists) 1-3, 90 volunteer patients. In preoperative evaluation, the remaining 3 ml of blood was centrifuged from the routine received blood to determine the level of vitamin D will be kept. Postoperative will be applied to patient controlled analgesia to all patients for 24 hours. To determine the level of postoperative pain, the visual analog scale (VAS) will be used in the clock unit and at the service 6, 12 and 24 hours. In this study, the investigators aimed to test the hypothesis of relation to pain and opioid consumption in acute postoperative (24 hours) of perioperative low-vitamin D.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Volunteer, * Between the Ages Of 18-65, * Least Primary School Graduate, * Not Using Drugs That May Affect Cognitive Functions, * Non-Alcohol Substance Use, * Patients Without Psychiatric and Neurological Disease.

Exclusion criteria

* Those with known psychiatric disease and drugs, * Those with an important cardiovascular or central nervous system disease, * Patients with pain syndromes or routinely using opioid. Very urgent patients

Design outcomes

Primary

Measure	Time frame	Description
preoperative Vitamin D Level and postoperative pain in patients to undergo laparoscopic cholecystectomy operation	6 months	Correlations of preoperative Vitamin D Level between postoperative pain in patients undergoing laparoscopic cholecystectomy.to undergo laparoscopic cholecystectomy operation

Secondary

Measure	Time frame	Description
preoperative Vitamin D Level and opioid analgesic consumption	6 months	Correlations of preoperative Vitamin D Level between opioid analgesic consumption in patients undergoing laparoscopic cholecystectomy.to undergo laparoscopic cholecystectomy operation

Countries

Turkey (Türkiye)

Outcome results