Brain Injuries, Consciousness Disorder
Conditions
Brief summary
Precise description of behavioral signs denoting transition from unresponsive wakefulness syndrome/vegetative state (UWS/VS) to minimally conscious state (MCS) or emergence from MCS after severe brain injury is crucial for prognostic purposes. A few studies have attempted this goal but involved either non-standardized instruments, limited temporal accuracy or samples, or focused on (sub)acute patients. The objective of this study is to describe the behavioral signs that led to a change of diagnosis, as well as the factors influencing this transition, in a large sample of patients with chronic disorders of consciousness after severe brain injury.
Interventions
BEHAVIORALRehabilitation
Multidisciplinary rehabilitation
Sponsors
Universitat Politècnica de València
Hospitales Nisa
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* documented medical diagnosis of CRS-R-based diagnosis of UWS or MCS at admission to the neurorehabilitation program
Exclusion criteria
* none
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline score in the Coma Recovery Scale-Revised until study completion | From inclusion in the study until discharge or death, assessed up to 24 months | The Coma Recovery Scale-Revised consists of 29 hierarchically organised items divided into 6 subscales addressing auditory, visual, motor, oromotor, communication, and arousal processes. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline score in the Functional Independence Measure until study completion | From inclusion in the study until discharge or death, assessed up to 24 months | The Functional Independence Measure is an 18-item measurement tool that explores an individual's physical, psychological and social function |
| Change from baseline score in the Disability Rating Scale until study completion | rom inclusion in the study until discharge or death, assessed up to 24 months | The Disability Rating Scale is an 8-item measure that assesses disability of individuals with moderate to severe traumatic brain injury at a wide range of functional levels from coma through community living |
Countries
Spain
Outcome results
None listed