Liver Metastasis Colon Cancer
Conditions
Brief summary
Preoperative chemotherapy is often used for patients with colorectal cancer liver metastasis (CLM). Many small CLMs (\<=2cm) may disappear after chemotherapy, while most of these are still alive. Ultrasonography (US) is a common imaging modality for the intraoperative detection tumor. Sonazoid is new echo-contrast agent, which is more stable and sensitive for detecting of small tumor. Investigators initially this prospective study to compare the detection performance before and after using sonazoid.
Interventions
DIAGNOSTIC_TESTAfter sonazoid
0.015ml/mg sonazoid enhanced US to detection of liver metastases.
Sponsors
Sun Yat-sen University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Pathology confirmed colorectal adenocarcinoma * One or more liver metastases less than 2 cm * Multidisciplinary team recommend to perform preoperative chemotherapy * Have baseline EOB-MR before chemotherapy
Exclusion criteria
* Could not fulfill the criteria of no evidence of disease (NED) after hepatic resection/ablation/radiotherapy * With other malignancies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| sensitive of detection tumor | 6 months | Change of the sensitivity detection liver tumors when using sonazoid enhanced ultrasound |
Countries
China
Contacts
Primary ContactJiliang Qiu
Backup ContactXuzhi Pan
Outcome results
None listed