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Resin Infiltration Treatment for MIH

Clinical Evaluation of the Effect of Resin Infiltration Treatment on Hypomineralised Enamel Surfaces

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04685889
Enrollment
34
Registered
2020-12-28
Start date
2018-05-23
Completion date
2019-12-20
Last updated
2020-12-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior Teeth, Enamel Caries, Enamel Hypoplasia, Molar Incisor Hypomineralization

Keywords

molar incisor hypomineralisation, resin infiltration, discoloration, enamel, lesion

Brief summary

The investigators aimed to evaluate changes in mineralisation degree, colour, and size of the lesion after Icon® in permanent teeth with MIH in 6 months.

Detailed description

A total of 116 permanent central teeth of 37 patients were included in the study. Icon® was applied to teeth with MIH, while the healthy teeth received no treatment (control). Group I : Icon® resin infiltration treatment was performed on 58 permanent central teeth with MIH and evaluated before; immediately after; and 1, 3, and 6 months after the procedure. Group II (Control Group): No treatment was performed on healthy teeth. However, similar to the treated teeth, 58 healthy permanent central teeth of the same individuals were evaluated before; immediately after; and 1, 3, and 6 months after the procedure. Lesions were evaluated before, immediately after, and 1, 3, and 6 months after treatment. Mineralisation degree of MIH lesions was evaluated using DIAGNOdent Pen, changes in the lesion colour and lesion size were evaluated using VITA EasyShade and the cross polarization technique, respectively.

Interventions

PROCEDUREResin infiltration

A sufficient amount of HCl was applied to the lesion using the icon etch syringe included in the set and was allowed to sit for 2 minutes. After washing with water for 30 seconds, the tooth was dried using an air spray. Once the enamel surface appeared chalky, Icon® dry application was initiated. Ethanol was applied to the lesion using the Icon® dry syringe included in the set, and after 30 seconds it was dried using an air spray. Sufficient amount of resin infiltrant was applied to the lesion using the Icon® infiltrant syringe. The resin infiltrant was applied to the lesion surface by massaging with the tip of the syringe in circular movements for 3 minutes such that it penetrates the surface thoroughly. The resin infiltrant was polymerized for 40 seconds with a light device.

Sponsors

Tokat Gaziosmanpasa University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
8 Years to 14 Years
Healthy volunteers
Yes

Inclusion criteria

* Molar incisor hypomineralisation on the labial surface of permanent central teeth Least one of the labial surface of the permanent anterior teeth were affected by MIH.

Exclusion criteria

* Dental caries and filling on anterior teeth. * Dental anomaly on anterior teeth. * Undergoing orthodontic treatment. * Periodontal diseases. * Cognitive and behavioural problems.

Design outcomes

Primary

MeasureTime frameDescription
Changes in the Mineralisation degreeBaseline (before resin infiltration), immediately after resin infiltration, 1 month later, 3 months later, 6 months laterMIH lesions was evaluated using DIAGNOdent Pen (laser fluorescence)
Changes in the lesion colourBaseline (before resin infiltration), immediately after resin infiltration, 1 month later, 3 months later, 6 months laterChanges in the MIH lesions colour was evaluated using VITA EasyShade (Spectrophotometers are equipped with sensors that can measure in many wavelengths)
Lesion size evaluated using cross polarization techniqueBaseline (before resin infiltration), immediately after resin infiltration, 1 month later, 3 months later, 6 months laterChanges in the MIH lesions size was evaluated using cross polarization technique

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 9, 2026