Meningitis, Meningococcal, Sequela
Conditions
Brief summary
While the initial evolution of meningococcal meningitis (MM) is well described, there are few data on the long-term evolution, beyond 1 year. The objective of this research is to evaluate the sequelae of MM beyond 1 year in patients with a history of MM followed in Paris area, France. Most children with MM in France have been included in the MM register and are still being followed. Parents will be offered a detailed clinical evaluation of their child including: a clinical and neurological examination, a cognitive performance assessment, an auditory, speech and visual assessment and an evaluation of the child's progress at school.
Interventions
OTHERsequela evaluation
clinical and neurological examination, psychological evaluation (cognitive performance), an auditory, speech and visual assessment and an evaluation of the child's school performance
Sponsors
Association Clinique Thérapeutique Infantile du val de Marne
Centre Hospitalier Intercommunal Creteil
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 17 Years
Healthy volunteers
No
Inclusion criteria
* Infants and children from 0 to 17 years old * Having had meningitis or meningococcal purpura fulminans between 2010 and 2021 * Delay ≥ 1 year between the date of diagnosis of meningitis or purpura meningococcal fulminans and the date of inclusion in the study (signature of the informed consent) * The holders of parental authority have read and understood the information letter and their express consent has been obtained * Patient affiliated to a social security system (Social Security or Universal Medical Coverage)
Exclusion criteria
* refusal to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of children with at least one neurological, orthopedic or sensory sequelae | 1 year |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of children with orthopedic complications | 1 year | — |
| Number of children with sensory disorders | 1 year | — |
| Number of children with skin sequelae | 1 year | — |
| Number of children with severe neurological sequelae | 1 year | — |
| Number of children with cognitive or psychological difficulties identified on the WPPSI, WISC V or VINELAND depending on their age and capacity | 1 year | 95% of the population has a Total IQ between 70 and 130 (from low intelligence to high intelligence). |
| Number of consultations during follow-up | 1 year | — |
| Post-traumatic stress in parents using the IES-R questionnaire | 1 year | A score up to 33 is associated with a stress post traumatic |
| Number of children with learning disabilities | 1 year | — |
Countries
France
Outcome results
None listed