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C-reactive Protein Levels in Acute Apical Abscess Due to Root Canal Infection

Assessment of C-reactive Protein Levels in Acute Apical Abscess Due to Root Canal Infection

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04684407
Enrollment
200
Registered
2020-12-24
Start date
2020-11-01
Completion date
2022-12-01
Last updated
2020-12-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentoalveolar Abscess

Brief summary

C-reactive protein levels of patients with acute apical abscess are evaluated before and after root canal treatment

Detailed description

In patients with acute apical abscess C-reactive proteins are evaluated before and after root canal treatment. In this intra-canal medications calcium hydroxide and triple antibiotic paste are compared. PAI score of the corresponding tooth is noted .

Interventions

PROCEDUREROOT CANAL TREATMENT

TWO TYPE OF INTRA CANAL MEDICATION PLACEMENT

Sponsors

CSI College of Dental Sciences and Research, Madurai
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
16 Years to 70 Years
Healthy volunteers
Yes

Inclusion criteria

patient with acute apical abscess

Exclusion criteria

* Teeth with evidence of previous initiated root canal treatment * History of myocardial infarction, coronary heart disease * Patients allergic to local anesthetic * Patients under steroid medication * Patients who are immunocompromised

Design outcomes

Primary

MeasureTime frameDescription
Post root canal C reactive protein level2 weeksPre-operative serum c-reactive protein level was measured to which the post operative c-reactive protein level after 2 weeks of root canal treatment are compared. The normal serum c-reactive protein level is 0 - 6.00 mg/L.

Secondary

MeasureTime frameDescription
pain and swelling assessment6 monthspain and swelling reduction after root canal treatment is assessed. . Pain is evaluated using visual analgue scale (VAS) , regarding swellling reduction patient is asked to evaluate subjectively whether the patient profile has returned to normal after the treatment and they were asked how many days it took for the swelling to resolve completely.

Countries

India

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026