Depression, Medication Adherence
Conditions
Brief summary
The acute and remission depression patients of 18-65 years old were recruited. At the time of enrollment, the demographic, symptomatic, neuropsychological and medication adherence data was collected. After the completion of the baseline assessment and examination, the patients were given antidepressant treatment or antidepressant treatment combined with Internet-based interventions. Clinical evaluation was performed at 1, 3 months (acute patients) and 6, 12 months (remission patients) after treatment, including the medication adherence, therapeutic efficacy, recurrence rate and functional rehabilitation. Through above work, this research is expected to provide clinicians with a set of Internet generalized technologies to improve the compliance and clinical outcomes of patients with depression, and to provide patients with treatment and management of the entire disease cycle.
Interventions
DRUGantidepressant treatment
depression recieve antidepressant treatment
OTHERantidepressant treatment combined with Internet-based interventions
depression recieve antidepressant treatment combined with Internet-based interventions
Sponsors
Peking University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* age 18-65 years old, acute (HAMD17 \> 17) and remission (HAMD17 \< 8) depression
Exclusion criteria
* other mental illnesses, serious somatic illnesses
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| HAMD17 reduction ratio | 3 months | The difference of HAMD17 reduction ratio between the two groups was compared |
| recurrence rate | 12 months | The difference of recurrence rate between the two groups was compared |
Countries
China
Contacts
Primary ContactYunai Su, MD
Backup ContactJitao Li, MD
Outcome results
None listed