Brain Injuries, Decompressive Craniectomy, Treatment Outcome
Conditions
Keywords
Decompressive craniectomy, Outcome, Brain injuries, Aneurysmal subarachnoid hemorrhage, Cerebral venous thrombosis, Intracerebral hemorrhage, Ischemic stroke, Traumatic brain injury
Brief summary
Decompressive craniectomy is a treatment of refractory intracranial hypertension after various etiologies : malignant ischemic stroke, traumatic brain injury, intraparenchymal hemorrhage, aneurysmal subarachnoid hemorrhage, cerebral venous thrombosis. Initially considered as a lifesaving therapy, benefits in terms of survival were shown compared to medical treatment alone. However, despite a better survival, morbidity and poor neurological outcome are frequent among survivors. The objective of the study is to identify initial good neurological outcome factors after decompressive craniectomy in a large series of patients, in order to argue surgical and intensive care decisions, considering expected benefit and quality of life.
Interventions
PROCEDUREDecompressive Craniectomy
Sponsors
Central Hospital, Nancy, France
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients undergoing a decompressive craniectomy from 06/11/2008 to 06/15/2018 in CHRU Nancy, France.
Exclusion criteria
* Infectious ou malignant disease leading to decompressive craniectomy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Good neurological outcome | 6 months after surgery | The neurological outcome is considered good when Glasgow Outcome Score extended (GOSE) assessed 6 months after decompressive craniectomy is between 5 and 8. |
Countries
France
Outcome results
None listed