Study of the Evolution Profile of the Renal Doppler in the Perioperative Hepathic Transplantation

Study of the Evolution Profile of the Renal Doppler in the Perioperative Hepathic Transplantation - Interest in Predicting the Occurence of Acute Postoperative Renal Faillure

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04682236

Acronym

DOP-RENAL

Enrollment

Registered

2020-12-23

Start date

2020-11-25

Completion date

2022-05-25

Last updated

2020-12-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Renal Failure

Keywords

Acute Renal Failure, Chronic renal failure, Liver transplant, Renal vascular profiles, Intraoperative hemodynamic instability, Acute tubular necrosis, Renal doppler

Brief summary

Liver transplantation is associated with a modification of the perfusion pressures of the abdominal organs (preoperative portal hypertension in connection with liver pathology, and normalization of the perfusion pressures during surgery). This abrupt change in the infusion regime is probably responsible for an alteration in renal function in some patients, and the identification of renal vascular profiles using Doppler could point to pathological profiles, which should be diagnosed early.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patient of full age (≥18 years) * Patient operated on at the HUS for a liver transplant, between July 1, 2019 and June 30, 2020. * Patients having undergone an evaluation of hepatic and renal vascular profiles perioperatively. * Patients hospitalized in the surgical intensive care unit after hepatic transplant surgery. * Patient not having expressed, after information, the reuse of his data for the purposes of this research

Exclusion criteria

* Patient who expressed his opposition to participating in the study * Patient with suspected obstructive acute renal failure * Stenosis of renal arteries known at the time * End-stage renal disease on dialysis * Impossibility of giving the subject informed information (difficulties in understanding the subject, etc.) * Subject under safeguard of justice

Design outcomes

Primary

Measure	Time frame
Retrospective analysis of the development profiles of renal dopplers in perioperative liver transplantation	Files analysed retrospectily from July 1st, 2019 to June 30, 2020 will be examined

Countries

France

Contacts

Primary ContactJulien POTTECHER, MD, PhD

julien.pottecher@chru-strasbourg.fr33 3 88 12 70 95

Backup ContactSaïd CHAYER, PhD, HDR

said.chayer@chru-strasbourg.fr33 3 88 11 66 90

Outcome results