Hypertension
Conditions
Brief summary
WeChat is the largest and most popular social media platform in China, In this study, investigators will evaluate the use of management program delivered via WeChat platform in patients with hypertension.
Interventions
OTHERWeChat platform group
Participants in the intervention group will receive educational messages related to hypertension, such as impact of hypertension on cardiovascular system, lifestyle adjustment and side effects of antihypertensive drugs. Participants will be reminded to take their blood pressure regularly and enter the blood pressure readings into the WeChat platform. If participants enter extremely high or low readings, they will be asked to seek medical help from doctors. Participants can also consult doctors online via WeChat platform by text and voice messages, or voice calls.
Sponsors
First Affiliated Hospital of Wenzhou Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients aged ≥ 18 years with confirmed diagnosis of hypertension * Office systolic blood pressure (SBP)≥140 mmHg and/or diastolic blood pressure (DBP)≥90 mmHg, or ambulatory blood pressure monitoring (ABPM) indicating 24- hour SBP ≥130 mmHg and/or DBP ≥80 mmHg and/or daytime SBP ≥135 mmHg and/or DBP ≥85 mmHg and/or nocturnal SBP ≥120 mmHg and/or DBP ≥70 mmHg. * Patients have smart phone and often use WeChat to communicate with others (including written interaction) * Patients are willing and able to give informed consent for participation in the trial
Exclusion criteria
* Secondary hypertension * Hypertensive emergency: defined as severe elevations in BP (SBP ≥180 mmHg and/or DBP≥120mmHg) associated with evidence of new or worsening target organ damage, including hypertensive encephalopathy, intracranial hemorrhage, cerebral hemorrhage, subarachnoid hemorrhage, cerebral infarction, heart failure, acute coronary syndrome (unstable angina, acute myocardial infarction), aortic dissection, perioperative hypertension, preeclampsia, and eclampsia * Refractory hypertension: defined as failure to control BP despite lifestyle changes and use of at least 5 antihypertensive agents of different classes, including a thiazide-type diuretic and a mineralocorticoid receptor antagonist * Pregnancy or lactation or having pregnancy plan during the study period * Life expectancy less than 1 year * Participation in another clinical study or clinical trial in the 3 months prior to the confirmation of eligibility or current user of WeChat platform provided by hypertension center of the first affiliated hospital of Wenzhou medical university
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Proportion with controlled blood pressure at 12 months (defined by ambulatory blood pressure monitoring ) | 12 months | mean 24-hour ambulatory blood pressure monitoring (ABPM) \<130/80 mmHg, day time blood pressure \<135/85 mmHg, and nocturnal blood pressure \<120/70 mmHg |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Systolic blood pressure (mmHg) at 12 months | 12 months | Systolic blood pressure (mmHg) at 12 months |
| Diastolic blood pressure (mmHg) at 12 months | 12 months | Diastolic blood pressure (mmHg) at 12 months |
| Medication adherence at 12 months | 12 months | Medication adherence will be measured by 8-item self-reported medication-taking scale |
Contacts
Primary ContactGaoJun Wu
Outcome results
None listed