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Molecular Mechanisms of Tooth Eruption

Molecular Mechanisms of Tooth Eruption

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04675203
Enrollment
50
Registered
2020-12-19
Start date
2021-03-31
Completion date
2023-01-31
Last updated
2021-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth Eruption

Brief summary

The main objective is to study the expression of molecules involved in tooth morphogenesis and eruption in healthy patients, and then to compare them with the results in patients with abnormalities of eruption (results obtained via a collection of biological samples of rare diseases already authorized).

Interventions

PROCEDURETooth extraction

Tooth extraction

Sponsors

University Hospital, Strasbourg, France
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
12 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patient over 12 years old who has given his consent * Patient whose legal representatives have given their consent for the use of operating waste destined for incineration * Patient undergoing oral surgery at the University Hospitals of Strasbourg, at the origin of the production of surgical waste such as teeth and bone fragments * Patient affiliated to a social security system

Exclusion criteria

* Refusal to participate * Patient with chronic systemic pathology * Patient under long-term drug treatment * Patient presenting a rare pathology with oral manifestation * Patient with a history of chemotherapy or head and neck radiotherapy * Non-French speaking patient / inability to give informed information * Patient under guardianship, curatorship or legal protection

Design outcomes

Primary

MeasureTime frameDescription
Expression and localization of molecules involved in tooth eruptionDuring surgeryTissues are collected at the time of surgery and transferred during the day to the laboratory for analysis

Countries

France

Contacts

Primary ContactMarion STRUB
marion.strub@chru-strasbourg.fr+33 3 88 69 56

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026