Pleural Effusion, Malignant, Prognosis
Conditions
Brief summary
This study aims to evaluate the clinical course of patients diagnosed with pleural effusion and determine various clinical factors and biomarkers associated that can predict the diagnosis and clinical outcome and prognosis of patients with pleural effusion due to specific causes.
Detailed description
Patients who presented to Seoul National University Bundang Hospital with pleural effusion would be recruited. Pleural fluid and blood samples would be collected. All patients will receive routine diagnostic procedures and medical care and treatments according to the diagnosis; the original cancer if diagnosed with malignant effusion, and managements for pleural effusion control. Patients would be observed for the clinical course and prognosis up to 3 years without any interventions caused by this study.
Interventions
None listed
Sponsors
Seoul National University Bundang Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients presented with pleural effusion * Patients who undergo thoracentesis and fluid analysis for diagnosis and management
Exclusion criteria
* Patients who refuse to be enrolled
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mortality | From date of diagnosis of malignant pleural effusion until the date of death, assessed up to 36 months. | Mortality |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Disease progression | From date of diagnosis of malignant pleural effusion until the date of first documented disease progression, assessed up to 36 months. | Progression of original malignancy or new metastasis occured |
Countries
South Korea
Contacts
Primary ContactYeon Wook Kim, Professor
Outcome results
None listed