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Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery

Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery

Status
Active, not recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04670224
Acronym
QLB
Enrollment
286
Registered
2020-12-17
Start date
2021-03-16
Completion date
2026-01-31
Last updated
2025-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominoplasty, Analgesia, Locoregional Anesthesia, Quadratus Lumborum Block

Keywords

Quadratus lumborum block, Abdominoplasty, Analgesia, Locoregional Anesthesia

Brief summary

Abdominoplasty is a common surgical procedure in plastic surgery which causes postoperative pain and may delay patients' recovery. Surgery is potentially associated with a number of postoperative complications, whether cardiovascular, respiratory, infectious, thromboembolic, or digestive … Although they do not inevitably lead to a life-threatening prognosis, in many cases these complications delay post-operative recovery. Defined in the 1990s by Professor Henry Kehlet's Danish team, rapid rehabilitation after planned surgery is an approach to overall patient care that aims to rapidly restore previous physical and mental capacities and thus significantly reduce mortality and morbidity. Pain management is at the heart of this program and local anesthesia techniques are at the heart of early rehabilitation programs. Described for just over a decade, Quadratus Lumborum Block (QLB) have shown their effectiveness for analgesia in abdominal, or orthopedic, or obstetrical surgery. Considering the anatomical territory concerned, this locoregional anesthesia technique seems to be very interesting in abdominoplasty to allow early rehabilitation of the patient.

Interventions

OTHERQLB anesthesia

The QLB is a bilateral locoregional anesthesia technique, performed after surgery, under general anesthesia and in right and then left lateral decubitus.

OTHERIntravenous anesthesia without QLB

only intravenous anesthesia

Sponsors

Centre Hospitalier Universitaire, Amiens
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult patients admitted for programmed dermo-lipectomy surgery with or without associated liposuction.

Exclusion criteria

* Pregnant woman * Patient under 18 years of age * Subject under guardianship or curators * Patient allergic to local anesthetics * Infection at the puncture sites * Patient on morphine analgesic over the long term * Patient on antidepressants for neuropathic pain.

Design outcomes

Primary

MeasureTime frame
Variation from baseline of morphine consumption24 hours after surgery

Secondary

MeasureTime frame
Variation from baseline of morphine consumption1 hour after surgery

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026