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Impact of Respiratory Rehabilitation on Quality of Life in Patients With Hyperventilation Syndrome

Impact of Respiratory Rehabilitation on Quality of Life, Measures by the SF-36 Score, in Patients With Hyperventilation Syndrome: Crossover, Prospective and Randomized Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04668638
Acronym
RESPIR-HVS
Enrollment
44
Registered
2020-12-16
Start date
2021-03-10
Completion date
2025-07-01
Last updated
2025-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperventilation Syndrome

Keywords

Hyperventilation syndrome, Respiratory rehabilitation, Quality of Life

Brief summary

The hyperventilation syndrome is a quite frequent pathology, affecting up to 10% of the general population and 40% of the asthmatic population. Its physiopathology is still badly known and even if it is a benign affection, its associated comorbidities and symptomatology greatly decrease the patients' quality of life. Yet, no medicinal treatments have been proved useful, but prescribers noticed improvements after physiotherapy. Given that the physiotherapy impact on hyperventilation syndrome is not well described in the literature, this study aims to scientifically ascertain physiotherapy benefits on quality of life and symptomatology in hyperventilation syndrome-suffering patients.

Interventions

Respiratory rehabilitation includes education, hypoventilation exercises, diaphragmatic breathing exercises, relaxation, retraining, others.

Sponsors

Centre Hospitalier Régional d'Orléans
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Outcomes Assessor)

Intervention model description

Patients will be divided into two groups: * Group 1 (Control Group) will not immediately receive respiratory rehabilitation but between the 2nd and 4th months postdiagnosis. * Group 2 (Intervention Group) will immediately receive rehabilitation between the diagnosis and the 2nd month postdiagnosis.

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Positive hyperventilation syndrome diagnosis * Having a social security insurance * Being at least 18 years old * Having given their written consent

Exclusion criteria

* Being put under guardianship or curatorship * Having seen a physiotherapist for a respiratory rehabilitation in the last three months * Suffering from a chronic and degenerative pathology (chronic obstructive pulmonary disease, Parkinson's disease, idiopathic fibrosis, …) * Not being able to receive the respiratory rehabilitation from our care providers * Already having received a rehabilitation for hyperventilation syndrome * Not speaking French or not being unable to complete the questionnaires

Design outcomes

Primary

MeasureTime frameDescription
Incidence of respiratory rehabilitation on Quality of lifeDay 0Quality of life will be evaluated with the SF-36 score

Secondary

MeasureTime frameDescription
Change in symptomatologyDay 0Change in symptomatology will be evaluated on the Nijmegen questionnaire

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026