Inspiratory Effort in COVID-19

Inspiratory Effort Assessment in Patients With COVID-19 Pneumonia Undergoing Non Invasive Respiratory Support

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04666246

Acronym

PERSIA

Enrollment

Registered

2020-12-14

Start date

2020-03-01

Completion date

2030-02-01

Last updated

2025-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Failure, Covid19

Keywords

Acute respiratory failure, Esophageal pressure, Non invasive respiratory support, COVID-19

Brief summary

This study aims at assessing esophageal pressure in patients with acute respiratory failure due to COVID-19 undergoing non invasive respiratory support.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* COVID-19 * Acute respiratory failure undergoing non-invasive respiratory support

Exclusion criteria

* Need for immediate endotracheal intubation * Chronic respiratory diseases

Design outcomes

Primary

Measure	Time frame	Description
Inspiratory effort quantification	24 hours from admission	Esophageal pressure assessment through dedicated esophageal pressure transducer

Secondary

Measure	Time frame	Description
Non invasive respiratory support failure	24 hours	Reaching of the criteria for endotracheal intubation

Countries

Italy

Contacts

Primary ContactRoberto Tonelli, MD

roberto.tonelli@me.com0039 0594225934

Backup ContactAlessandro Marchioni, MD

marchioni.alessandro@unimore.it0039 0594225859

Outcome results