Validation of COVILUS Score in Patients Suspected of COVID-19 Infection in the Emergency Room

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04666064

Acronym

COVILUS2

Enrollment

100

Registered

2020-12-14

Start date

2020-12-10

Completion date

2021-04-28

Last updated

2021-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid19, Lung Ultrasound, Respiratory Complication

Keywords

Covid19, lung ultrasound, Respiratory Complication, triage

Brief summary

Covid-19 (English acronym meaning coronavirus disease 2019) is an emerging infectious disease caused by a strain of coronavirus called SARS-CoV-2. The current pandemic has resulted in a significant number of admissions in the emergency room (ER) due to suspicion of COVID-19 infection. Use of lung ultrasound is standard practice to diagnose acute respiratory failure in ER. Recently, typical lung ultrasonographic characteristics of COVID-19 disease has been described. The investigators demonstrated that the association of 4 signs in pulmonary ultrasound associated with a clinical sign (COVILUS score) could predict the occurrence of a positive RT-PCR in patients suspected of COVID-19 infection admitted to the emergency room. The investigators are going to conduct a new study to validate this COVILUS score in this type of patient. The main objective will be to validate the diagnostic performance of lung ultrasound in patients admitted to the emergency room with suspected COVID19 infection.

Interventions

DIAGNOSTIC_TESTCovid19 RT-PCR

patients admitted to ER for suspicion of COVID-19 infection will have a SARS-CoV-2 RT-PCR test

OTHERlung ultrasound

patients admitted to ER for suspicion of COVID-19 infection who has a SARS-CoV-2 RT-PCR test and for whom the emergency doctor decide to perform a lung ultrasound

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients admitted to ER for suspicion of COVID-19 infection who has a SARS-CoV-2 RT-PCR test and for whom the emergency doctor decide to perform a lung ultrasound as part of the BLUE protocol * Age\> 18 years old

Exclusion criteria

* patients \< 18 years of age * patients under guardianship or curators * pregnancy * poor echogenicity due to the presence of an acoustic barrier (pneumothorax, subcutaneous emphysema, etc.) * patients with a suspected or proven acute lung disease (pneumonitis, acute respiratory distress syndrome (ARDS)) * patients with chronic interstitial lung disease * patients who will refuse to give their consent.

Design outcomes

Primary

Measure	Time frame
concordance between Covid19 RT-PCR results and lung ultrasound results	one week

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026