Male Reproduction COVID Sequelae Study (MARCOS).

Corona Virus Disease 19 (COVID-19) Vaccine and Impact on Fertility Study

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04665258

Enrollment

Registered

2020-12-11

Start date

2020-12-14

Completion date

2023-11-28

Last updated

2023-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility, Male

Keywords

COVID-19 Vaccine

Brief summary

The purpose of this study is to investigate the effects of COVID-19 Vaccination on semen parameters and to determine how long these possible changes may last following vaccination.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

MALE

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

1. Receiving COVID-19 vaccines 2. Male age 18-50 years old

Exclusion criteria

1. Adults unable to consent 2. Women 3. Prisoners 4. Men who have been receiving Testosterone replacement therapy or anabolic steroids within the last year 5. Men with a history of Azoospermia 6. Men with a genetic or other medical condition known to be associated with decreased semen parameters (i.e. Klinefelter's syndrome, Y-Chromosome Microdeletion (YCMD), post-chemotherapy treatment, etc.) 7. Positive COVID-19 test within the last 3 weeks

Design outcomes

Primary

Measure	Time frame	Description
Sperm concentration	up to 6 months	As measured from semen samples.
Sperm motility	up to 6 months	As measured from semen samples.

Outcome results