Endometriosis, Obstetric Complication
Conditions
Keywords
Endometriosis, Obstetric outcome, Delivery outcome, Neonatal outcome
Brief summary
The purpose of this study is to assess if endometriosis can be considered a risk factor for adverse obstetric and delivery outcomes
Detailed description
This is a retrospective, observational, case-control study. Pregnancy, delivery and neonatal outcomes will be analyzed in two groups of patients (case and control group): women with diagnosis of endometriosis histologically confirmed and women without endometriosis. Women with endometriosis will be matched to controls by age. A database with general medical and gynecological history, pregnancy course, delivery mode and newborn conditions will be analyzed.
Interventions
OTHERRetrospective analysis of obstetrics outcomes
Retrospective analysis of clinical records including general medical and gynecological history, pregnancy course, delivery mode and newborn conditions.
Sponsors
Azienda Ospedaliero-Universitaria di Modena
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
* Pregnant women who delivered at Azienda Ospedaliero Universitaria Policlinico di Modena from 2000 to 2020 * Histologic diagnosis of endometriosis before pregnancy for case group * Age matched healthy patients for control group
Exclusion criteria
* Clinical records not available
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Preterm delivery | Time of delivery | Incidence of delivery before 37 weeks of pregnancy |
| Gestational diabetes | after 18 weeks' pregnancy | fasting blood glucose \>17 mmol/L |
| Gestational hypertension | after 20 weeks' gestation | blood pressure persistently \> 140/90 mm Hg |
| Assisted reproduction technologies | before pregnancy | Patients who referred to assisted reproduction technologies |
| Cesarean Section | Time of delivery | Robson Classifications |
| Postpartum hemorrhage | Time of delivery | Greater than 500 mL estimated blood loss in a vaginal delivery or greater than 1000 mL estimated blood loss at the time of cesarean delivery |
| Birth-weight | Time of delivery | small for gestational age (birth weight below the 10th percentile) or large for gestational age (birth weight over the 90th percentile) |
| Apgar scores | Time of delivery | Apgar scores |
Countries
Italy
Contacts
Primary ContactCarlo Alboni
Outcome results
None listed