Intraoperative Conversion During Video-assisted Thoracoscopy Resection for Lung Cancer Does Not Alter Survival

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04663191

Acronym

ICVATR

Enrollment

843

Registered

2020-12-10

Start date

2020-01-02

Completion date

2020-12-03

Last updated

2020-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lobectomy, Lung Cancer, Surgery, Survival, Video-assisted Thoracoscopic Surgery

Keywords

video-assisted thoracoscopic surgery, lung-cancer surgery, intraoperative conversion to open surgery, lobectomy, survival

Brief summary

Anatomical resection with systematic lymph-node dissection is currently the standard of care for the treatment of early stage non-small cell lung cancer. The use of minimally invasive approaches has increased greatly over the last two decades \[either video-assisted thoracoscopic surgery (VATS) or robotic-assisted thoracoscopic surgery (RATS)\], as they provide the patient with better outcomes than open thoracotomy. Minimally invasive VATS lobectomy for a standard case is generally a straightforward procedure for a well-trained surgical team, although concomitant preoperative pathologies or intraoperative findings/adverse events may result in technical difficulties, leading to intraoperative conversion, commonly by thoracotomy. The investigators aimed to assess long-term outcomes in a consecutive cohort of patients treated by anatomical pulmonary resection either using VATS, VATS requiring intraoperative conversion to thoracotomy, or upfront open thoracotomy for lung-cancer surgery.

Interventions

PROCEDUREanatomical resection

Anatomical resection with systematic lymph-node dissection

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* All consecutive patients treated by anatomical lobar pulmonary resection (lobectomy, bilobectomy) or anatomical sublobar pulmonary resection (segmentectomy) for non-small cell lung cancer (NSCLC), either by VATS (eventually with intraoperative conversion) or upfront thoracotomy.

Exclusion criteria

* patients with non-anatomical pulmonary resection (wedge resection) * patients with a histology other than NSCLC (benign or metastatic from another primitive cancer), stage IV NSCLC disease, * patients with multiple primary NSCLC (synchronous or metachronous) * patients with incomplete resection (R+) * patient for whom a VATS approach was never considered

Design outcomes

Primary

Measure	Time frame
Overall survival during the follow-up period after surgery	from day of surgery up to 7 years

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026