Xerostomia
Conditions
Keywords
paraffin chewing gum, sialometry, salivary flow rate, mouth dryness
Brief summary
The study examines two different chewing gums with regard to consistency and its influence on the result of sialometry
Detailed description
The examination (sialometry) is performed on healthy volunteers. The volunteers must chew on a paraffin gum for seven minutes. After each minute, the amount of secreted saliva is spat into a designated cup and evaluated. This test is performed with Aurosan chewing gum and later with GC Europe chewing gum.
Interventions
DIAGNOSTIC_TESTParaffin Pellets from Aurosan GmbH
1 to 2 minutes pre-chewing time chewing Paraffin Pellets from Aurosan GmbH, after which the amount of saliva is collected over a period of five minutes. The patient may chew the chewing gum once per second; after each minute the produced amount of saliva is spit in a cup, the whole amount measured after 5 minutes.
DIAGNOSTIC_TESTChewing wax from the Saliva-Check Buffer from GC Europe
1 to 2 minutes pre-chewing time chewing wax from the Saliva-Check Buffer from GC Europe, after which the amount of saliva is collected over a period of five minutes. The patient may chew the chewing gum once per second; after each minute the produced amount of saliva is spit in a cup, the whole amount measured after 5 minutes.
Sponsors
University Hospital, Basel, Switzerland
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
Determination of salivary flow rate chewing Paraffin pellets (manufactured by Aurosan GmbH) for 7 minutes. At a later timepoint determination of salivary flow rate chewing Saliva-Check Buffer (manufactured by GC Europe) for 7 minutes.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* healthy volunteers * non-smoker * no medication
Exclusion criteria
* physical or mental illnesses * smokers * regular medication intake * pregnant women * dementia or persons who are unable to judge or persons with guardianship * minor test persons
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Stimulated salivary flow rate (ml) | at baseline (approx 40 minutes) | Comparing measurements of stimulated salivary flow rate (ml) after chewing two different chewing gums |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in consistency of chewing gum | at baseline (7 minutes for each chewing gum) | Change in consistency (compressive strength, measured in Newton) of the chewing gums for stimulated salivary flow rate measurement over a time period of 7 minutes chewing time |
Countries
Switzerland
Outcome results
None listed