Study of Iron Accumulation Measured in MRI in Non-pathological Aging

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04659824

Acronym

FER-IRM

Enrollment

190

Registered

2020-12-09

Start date

2023-01-30

Completion date

2029-01-31

Last updated

2025-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Aging

Brief summary

To study the correlation between the iron load in brain, measured in MRI, and the age of healthy subjects Secondary objectives are to study the correlations between the iron load in cortical brain regions and (i) the cognitive performances, (ii) markers of aging (MRI, EEG, OCT, biology),and (iii) demographical factors involved in iron load.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 95 Years

Healthy volunteers

Yes

Inclusion criteria

* Men or women between 18 and 95 years old * French speaker with capability to understand the instructions * Health insurance

Exclusion criteria

* Pregnancy * minor subject * no informed consent agreement * subject enrolled in pharmaceutic study or exclusion period * MRI contra-indications * Neurological or psychiatric disorders * MOCA \< 26 * Psychotropic drugs * More than 3 MRI exams * More than 1 neuropsychological assessment (same cognitive tests) in the last 12 months * Unable to follow the entire protocol according to the investigator

Design outcomes

Primary

Measure	Time frame
Correlation coefficient between iron load in MRI and age	baseline

Countries

France

Contacts

Primary ContactGrégory KUCHCINSKI, MD

gregory.kuchcinski@chru-lille.fr0320445962

Outcome results