Prevalence of Obstructive Sleep Apnea (OSA) and the Association With Cognitive Impairment

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04658290

Enrollment

500

Registered

2020-12-08

Start date

2020-08-29

Completion date

2026-08-28

Last updated

2024-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive Impairment, Obstructive Sleep Apnea

Brief summary

The study is aimed to carry out an epidemiology study investigating the prevalence of obstructive sleep apnea (OSA) and the association with cognitive impairment.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

40 Years to 74 Years

Healthy volunteers

Yes

Inclusion criteria

* Have stability of at least 4 weeks on permitted medications (i.e. medications known not to affect sleep architecture or circadian rhythms).

Exclusion criteria

* Suspected dementia or a score of \<24 on the mini-mental state examination * A diagnosis of neurological disorders (e.g. Parkinson's Disease, Epilepsy, Multiple Sclerosis) * Psychiatric disorders including current major depression; bipolar disorder; schizophrenia * Other known clinically significant sleep disorders (e.g. narcolepsy) * Been currently receiving CPAP or bi-level pressure for OSA

Design outcomes

Primary

Measure	Time frame
Number of subjects having apnea-hypopnea index of more than 5	1 year

Secondary

Measure	Time frame
incidence of cerebrovascular disease	5 years
Montreal Cognitive Assessment	5 years

Countries

Hong Kong

Outcome results