Breast Cancer
Conditions
Brief summary
The purpose of the study is to evaluate which is more effective resistance or aerobic exercises on cancer related fatigue and immunity in breast cancer patients undergoing adjuvant chemotherapy.
Detailed description
The problem of cancer related fatigue and decreased immunity, as a result of treatment with adjuvant chemotherapy in breast cancer patients is not well known. Fatigue and decreased immunity have a negative impact on work, social relationships, mood, and daily activities and cause significant impairment in overall quality of life, Furthermore the need of this study is developed from the lack of information in the published studies about the effect of the treatment with chemotherapy among breast cancer patients on inducing fatigue and decreasing immunity and the effect of resistance and aerobic exercises on improving these changes.
Interventions
DEVICETreadmill
Treadmill is not used to harness power, but as exercise machines for running or walking in one place. Rather than the user powering the mill, the machine provides a moving platform with a wide conveyor belt driven by an electric motor or a flywheel. The belt moves to the rear, requiring the user to walk or run at a speed matching that of the belt. The rate at which the belt moves is the rate of walking or running. Thus, the speed of running may be controlled and measured
OTHERresisted exercises
Resistance exercises will be involved in this technique are for upper and lower limb (Exercise program including shoulder flexion, abduction and horizontal adduction, elbow extension and flexion, calf raise, leg extension and squatting)
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
FEMALE
Age
30 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
\- The subject selection will be according to the following criteria: 1. Age range from 30-60 years. 2. Females post mastectomy only will participate in the study. 3. All patients undergoing adjuvant chemotherapy and have cancer related fatigue and decreased immunity. 4. All patients enrolled to the study will have their informed consent.
Exclusion criteria
* The potential participants will be excluded if they meet one of the following criteria: 1. Age more than 60 years or less than 30 years. 2. Another concurrent malignant disease. 3. Subjects suffering from any condition for which resistance or aerobic exercises contraindicated as metastasis, sever osteoporosis and cardiac diseases.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Fatigue assessment scale | The evaluation will be conducted during before the cycles | The Fatigue Assessment Scale (FAS) is quick and easy to complete for patients, and not time consuming. It is also helpful for physicians and other health care workers in the follow-up of their patients. The FAS has proven to be a valid questionnaire to assess fatigue in cancer patients, but also in many other patients with chronic diseases |
| Hemoglobin level test for fatigue assessment | he evaluation will be conducted before the cycles | Hemoglobin levels are measured by a blood test. Hemoglobin, or Hb, is usually expressed in grams per deciliter (g/dL) of blood. A low level of hemoglobin in the blood relates directly to a low level of oxygen |
| White blood cells count test for immunity assessment | he evaluation will be conducted before the cycles | White blood cells (also called leukocytes and abbreviated as WBCs) are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. All white blood cells are produced and derived from multipotent cells in the bone marrow known as hematopoietic stem cells. Leukocytes are found throughout the body, including the blood and lymphatic system |
Countries
Egypt
Contacts
Primary ContactLamiaa sa tolba, ASS.lecturer
Backup ContactAmal mo abdel baky, Professor
Outcome results
None listed