Thiol/Disulfide and Oxidative Stress

Evaluation of Saliva Thiol/Disulfide Homeostasis and Oxidative Stress in Children With Severe Early Childhood Caries by a Novel Method- Part 1

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04655859

Enrollment

Registered

2020-12-07

Start date

2020-05-10

Completion date

2020-09-15

Last updated

2020-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe Early Childhood Caries

Brief summary

The aim of this study was to evaluate the role of thiol/disulfide homeostasis and oxidative stress in the saliva of children with severe early childhood caries

Interventions

DIAGNOSTIC_TESTsaliva cotton swab

evaluate the role of thiol/disulfide homeostasis and oxidative stress in the saliva of children with severe early childhood caries and healthy group

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

3 Years to 5 Years

Inclusion criteria

* 3-5 years

Exclusion criteria

* the children with systemic illness, using anti-inflammatory drug

Design outcomes

Primary

Measure	Time frame	Description
thiol/disulfide homeostasis	six months	Unstimulated saliva samples were taken from all children. Then, thiol/disulfide homeostasis and antioxidant levels were evaluated.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026