Hypersensitivity, Drug
Conditions
Keywords
anaphylaxis, perioperative, hypersensitivity reactions, neuromuscular blocking agents, hypnotics
Brief summary
Perioperative hypersensitivity reactions are still associated with significant morbidity and mortality despite early recognition and use of epinephrine. The epidemiology of these reactions evolves over time and changes with clinical practice. The main objective is to study the epidemiology of these reactions over a 10-year period, including patient phenotype, reaction phenotype and outcome of the allergic work-up.
Interventions
None listed
Sponsors
University Hospital, Strasbourg, France
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
7 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Minor and major subject * Subject having experienced a perioperative hypersensitivity reaction between January the 1st 2017 and December the 31st 2027. * Referred for an allegro-anesthetic workup * Subject not having expressed his opposition, after information, to the reuse of his data for the purposes of this research.
Exclusion criteria
* Subject having expressed opposition to participating in the study * Inability to provide the subject with research information * Subject under guardianship or guardianship * Subject under safeguard of justice
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Retrospective analysis of incidence of all perioperative hypersensitivity reactions referred in an allegro-anesthetic | Outcome is analysed every 2 years over a 10 years period |
Countries
France
Contacts
Primary ContactPaul-Michel MERTES, MD, PhD
Backup ContactCharles TACQUARD, MD
Outcome results
None listed