Atrial Fibrillation
Conditions
Brief summary
This study is a single-center, prospective cohort study to investigate non-invasive method to assess left ventricular diastolic function using echocardiography. Patients with AF who are referred radiofrequency catheter ablation (RFA) will be included prospectively. Transthoracic echocardiography will be performed during, immediately before RFA and with no cardiovascular medication taken between the exams so that the loading conditions during catheterization and echocardiography are as similar as possible. We will validate previously proposed echocardiographic parameters and creat an algorithm to identify the relationship between echocardiographic parameters of diastolic function and invasively measured LA pressure in patients with atrial fibrillation.
Interventions
None listed
Sponsors
Yonsei University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult ≥ 19 year-old * Patients who scheduled to perform radiofrequency catheter ablation for atrial fibrillation * Patients who had paroxysmal, persistent, or chronic AF * Patients provided with the written, informed consent to participate in this study
Exclusion criteria
* Patients with prosthetic valve * Life expectancy \< 12 months * Subject who the investigator deems inappropriate to participate in this study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Association between mean left atrial pressure and echocardiographic parameters | up to 12 weeks after collecting all data | Correlation between echocardiographic parameters or algorithm to estimate invasively measured left atrial pressure. Echocardiographic parameters: E/A ratio, E velocity, e' velocity, E/e', IVRT. LV strain, RV strain,, LA strain, Vp, E/Vp, LA volume index, TV V max, and Peak acceleration rate of mitral E velocity |
Countries
South Korea
Contacts
Primary ContactJong-Won Ha
Outcome results
None listed