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Impact of Sarcopenia Index on Postoperative Pulmonary Complication in Elderly Patients Undergoing OPCAB

Impact of Sarcopenia Index on Postoperative Pulmonary Complication in Elderly Patients Undergoing OPCAB: a Retrospective Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04654663
Enrollment
605
Registered
2020-12-04
Start date
2020-12-07
Completion date
2021-01-15
Last updated
2021-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Occlusive Disease

Brief summary

Retrospective data collection. The aim of this study is to determine the effect of preoperative sarcopenia index on postoperative pulmonary complications in elderly patients undergoing off-pump coronary artery bypass graft surgery.

Interventions

None listed

Sponsors

Yonsei University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients who were 65 years of age or older at the time of surgery(off-pump coronary artery bypass graft surgery) * serum cystatin C and creatinine test results were valid within one week before surgery

Exclusion criteria

* Patients with chronic renal failure (estimated glomerular filtration rate less than 60) * Patients with acute kidney injury * Patients with respiratory tract infection within 1 month before surgery

Design outcomes

Primary

MeasureTime frameDescription
postoperative pulmonary complications : pneumoniaDuring the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.CXR with at least one of the following: infiltrate, consolidation, cavitation;plus at least one of the following: fever \>38 °C with no other cause, white cell count \<4 or\>12\*109 litre-1, \>70 yr of age with altered mental status with no other cause;-plus at least two of the following: new purulent/ changed sputum, increased secretions/suctioning, new/worse cough/dyspnoea/tachypnoea, rales/ bronchial breath sounds, worsening gas exchange.
postoperative pulmonary complications : prolonged ventilationDuring the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.Indicate whether the patient had prolonged post-operative pulmonary ventilation \> 24.0 hours. The hours of postoperative ventilation time include OR exit until extubation, plus any additional hours following reintubation.
postoperative pulmonary complications : reintubationDuring the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.Indicate whether the patient was intubated for the first time after leaving the OR from the initial procedure, or re-intubated during the hospital stay after the initial extubation.

Secondary

MeasureTime frameDescription
postoperative complications : Permanent strokeDuring the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.Indicate whether the patient has a postoperative stroke (i.e., any confirmed neurological deficit of abrupt onset caused by a disturbance in blood supply to the brain) that was confirmed on imaging or did not resolve within 24 hours.
postoperative complications : Renal failureDuring the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.Indicate whether the patient had acute renal failure or worsening renal function resulting in ONE OR BOTH of the following: 1\. Increase in serum creatinine level 3.0 x greater than baseline, or serum creatinine level ≥4 mg/dL , Acute rise must be at least 0.5 mg/dl 2. A new requirement for dialysis postoperatively.
postoperative complications : MortalityDuring the hospitalization in which the operation was performed, even if after 30 days.all deaths, regardless of cause, occurring during the hospitalization in which the operation was performed, even if after 30 days (including patients transferred to other acute care facilities)
postoperative complications : DeliriumDuring the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.Indicate whether the patient experienced postoperative delirium from OR Exit to ICU discharge.
postoperative complications : Reoperation due to bleeding/tamponadeDuring the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.Indicate whether the patient was reexplored for mediastinal bleeding with or without tamponade either in the ICU or returned to the operating room.

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026