Cancer
Conditions
Brief summary
Due to the changes in lifestyle caused by the COVID-19, it is a priority to provide multi-interactive digital platforms and social media for nutrition and exercise programs for cancer patients. A two-year serial program uses mixed study methods of longitudinal combined experimental study. We will investigate cancer frailty's current situation and track the frailty trends after cancer patients received different treatments. We will also invite experts to develop multi-interactive digital platforms of nutrition and performance-based tailored circuit training programs according to the cancer frailty survey. We will recruit 20-85 years of newly diagnosed or first-time recurrence cancer patients and stratified randomization assigned to evaluate nutrition and physical exercise intervention effectiveness. The measure indicators were treatment-related adverse events, nutritional status, frailty status, survival rate, and life quality.
Interventions
BEHAVIORALNutrition and Exercise Strategies
Multiple Interactive with Nutrition and Exercise Strategies
Sponsors
Tzu Chi University
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Intervention model description
Arm A: fix model of cycle exercise(online supervise) and routine nutrition consult Arm B: fix model of cycle exercise(online supervise) and online nutrition consult Arm C: individualize cycle exercise(online supervise) and routine nutrition consult Arm D: individualize cycle exercise(online supervise) and online nutrition consult
Eligibility
Sex/Gender
ALL
Age
20 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Aged from 20-85 years with histological confirmation malignancy. * Requiring treatment by surgery, chemotherapy, hormonotherapy, radiotherapy, or targeted therapy with a curative intention as estimated by oncologists. * First diagnosed or recurrence of head and neck cancer, esophageal cancer, colon/rectum cancer, lung cancer, AML, ALL, lymphoma, multiple myeloma.
Exclusion criteria
* Non-head and neck cancer, esophageal cancer, colon/rectum cancer, lung cancer, AML, ALL, lymphoma, multiple myeloma with first diagnosis or recurrence patients. * Eastern Cooperative Oncology Group test score\>2. * Serious psychiatric or cognitive problems, and functional disability leading to a total inability to walk.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Frailty trend | After treatment three-month | After treatment frailty condition |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Treatment-related adverse events | After treatment one month | CTCAE or Clavien-Dindo classification |
Other
| Measure | Time frame | Description |
|---|---|---|
| Survival | The OS was calculated from the date of diagnosis to the date of death or was censored at the date of the last follow-up (3 years from diagnosed) for surviving patients. | from diagnosed to the dead date |
Countries
Taiwan
Contacts
Primary ContactChu Hou Huang, PhD
Outcome results
None listed