Health Related Quality of Life, Veno-arterial Extra-Corporeal Membrane Oxygenation
Conditions
Brief summary
Extracorporeal Membrane Oxygenation (ECMO) is a salvage therapy used in patients with refractory cardiogenic shock. This rescue technique is associated to a high mortality rate and to many complications that can impact the quality of life of the survivors. The aim of this study is to evaluate the Health-related quality of life in adults after veino-arterial Extra-Corporeal Membrane Oxygenation. The quality of life will be evaluated thanks to several methods : the Short Form 36, the EQ 5D 5L and the return to work status. Then, the investigators will analyze by subgroup the quality of life according to the cardiogenic shock etiology and try to determine the risk factors of an altered quality of life. The investigators will also evaluate current comorbidities of the patient thanks to the Groll Index.
Interventions
OTHEREvaluation of quality of life, comorbidities and return to work status
Quality of life will be evaluated thanks to several methods: Short Form 36, EQ 5D 5L and return to work status Questionnaires will be evaluated through postal and phone call at least 12 months after ECMO.
Sponsors
University Hospital, Strasbourg, France
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 95 Years
Healthy volunteers
No
Inclusion criteria
* Adults \>18 years * Veno-arterial ECMO between April 2008 and December 2019 in NHC surgical intensive care of Strasbourg * Affiliated to the French social security system
Exclusion criteria
\- Patients under guardianship or with legal protection
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluation of health-related quality of life after veino-arterial ECMO | The quality of life will be evaluated from 1 to 12 years after the ECMO | Quality of life will be evaluated by Short Form 36 ( score 0 to 100) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Analysis by subgroup according to the cardiogenic shock etiology | The quality of life will be evaluated from 1 to 12 years after the ECMO | 5 subgroups will be assessed according to the cardiogenic shock etiology: post cardiac surgery, post cardiac ischemia, pulmonary embolism or other right ventricle dysfunction, other etiology |
| Research of risk factors of an altered quality of life | The quality of life will be evaluated from 1 to 12 years after the ECMO | 5 subgroups will be assessed according to the cardiogenic shock etiology: post cardiac surgery, post cardiac ischemia, pulmonary embolism or other right ventricle dysfunction, other etiology |
| Evaluation of the current comorbidities thanks to Groll index | The quality of life will be evaluated from 1 to 12 years after the ECMO | 5 subgroups will be assessed according to the cardiogenic shock etiology: post cardiac surgery, post cardiac ischemia, pulmonary embolism or other right ventricle dysfunction, other etiology |
Countries
France
Outcome results
None listed