Stem Cell Transplant Complications
Conditions
Brief summary
Cerebral palsy (CP) is the most common physical disability in childhood. CP comprises a heterogeneous group of disorders that are the result of a non-progressive disruption or injury that occurred during fetal brain development or within the first two years of life.
Detailed description
This disruption can result in spasticity, dystonia, muscle contractures, weakness and difficulty in coordination that ultimately affects the ability to control movements. Resultant activity limitations may affect gross motor movements, fine motor movements, speech and communication, as well as eating and drinking.
Interventions
OTHERstem cells
Intravenous and Intrathecal transplantation of specific populations of purified bone marrow-derived stem cells and mesenchymal stem cells.
Sponsors
AMR KHALIL ORTHOPEDIC SURGERY CENTER
Aljazeera Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
2 Years to 12 Years
Healthy volunteers
No
Inclusion criteria
* • Must be more than 2 year of age and less than 12 years of age at the time of screening for inclusion in the study. * Clinical evidence of a non-progressive motor disability due to brain dysfunction.
Exclusion criteria
* • Intractable seizures * Traumatic brain injury * Genetic disorder * Current Infection * Renal insufficiency * Hepatic disease * HIV+ (as demonstrated by positive blood test) * Immunosuppression
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in Motor Performance. | 6 months | the number of patients who will have changes in motor performance |
Countries
Egypt
Contacts
Primary Contactamr khalil
Outcome results
None listed