Bone Graft in Aseptic Subtrochanteric Nonunion

Is Open Bone Graft Always Necessary When Treating Subtrochanteric Nonunion With a Reamed Intramedullary Nail?

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04651647

Enrollment

Registered

2020-12-03

Start date

2008-01-01

Completion date

2019-11-01

Last updated

2020-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subtrochanteric Nonunion

Keywords

subtrochanteric nonunion; intramedullary nail; bone graft

Brief summary

This study aimed to compare the radiologic results between closed nailing without bone graft (BG) and open nailing with BG for subtrochanteric nonunion and to determine when open BG should be considered.

Detailed description

In this retrospective study, we investigated the patients who underwent surgical intervention for subtrochanteric nonunion between January 2008 and March 2018 in two institutions. The cases with infection, large bone defect, pathologic fracture, open fracture, previous surgery using plate, and follow-up less than 1 year were excluded. We compared the demographic details and radiologic results between patients who underwent the open procedure with BG (BG group) and the closed procedure without BG (non-BG group) as a historical control, and risk factors for the failure of revision surgery were evaluated.

Interventions

PROCEDURERevision surgery with / without open bone graft

Removal of previous implant and re-alignment and re-fixation using intramedullary nail with (bone graft group) / without (non bone graft group) open bone graft

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

32 Years to 82 Years

Healthy volunteers

Inclusion criteria

* Patients who underwent surgical intervention using intramedullary nailing for aseptic subtrochanteric nonunion

Exclusion criteria

* The cases with infection, large bone defect, pathologic fracture, open fracture, previous and revision surgery using plate, and follow-up less than 1 year

Design outcomes

Primary

Measure	Time frame	Description
bony union	The time when bone union was achieved after surgery	Union was defined as painless full weight bearing with the absence of fracture line or bridging callus across at least three cortices on the AP and lateral views.
risk factors for nonunion	One year after surgery	Determining when open procedure with bone graft should be considered by analyzing risk factors for nonunion.

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026