Aortic Valve Disease
Conditions
Brief summary
The CAvEAT study is a not for profit, international, multicenter study aimed to assess the feasibility of selective coronary angiography (CA) after Transcatheter Aortic Valve Implantation (TAVI), to investigate predictors of successful selective cannulation (anatomical, technical, etc.) and to investigate if there is a significant difference among different type of transcatheter valves in selective coronary cannulation.
Interventions
DEVICETranscatheter Aortic Valve Implantation
Replacement of the aortic valve of the heart through the blood vessels, delivered via one of several access methods.
Sponsors
Fondazione GISE Onlus
University of Padova
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Symptomatic aortic valve disease (stenosis or combined stenosis and regurgitation) candidate to TAVI according to local Heart Team evaluation, including valve-in-valve procedure due to degeneration of a previously implanted surgical bioprosthesis, who undergo coronary access in the same session of TAVI, immediately after transcatheter valve deployment (the procedures have to be consecutive); * Provision of signed informed consent; * Age ≥18 Years.
Exclusion criteria
* Chronic Kidney Disease stage IV-V (without dialytic treatment; otherwise, patients in dialytic treatment could be included); * Current participation in an interventional clinical study; * Age \< 18 years.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Successful selective cannulation of both coronary arteries | Immediately after TAVI | Successful selective cannulation of both coronary arteries |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Successful selective cannulation of only left coronary artery | Immediately after TAVI | Successful selective cannulation of only left coronary artery (and no cannulation or sub selective cannulation of the contralateral) |
| Successful selective cannulation of only right coronary artery | Immediately after TAVI | Successful selective cannulation of only right coronary artery (and no cannulation or sub selective cannulation of the contralateral) |
Countries
Italy
Contacts
Primary ContactMatteo Martinato, PhD
Outcome results
None listed