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The Effect of Fertility Health Awareness Strategies on Fertility Knowledge and Childbearing in Young Married Couples

The Effect of Fertility Health Awareness Strategies on Fertility Knowledge and Childbearing in Young Married Couples (FertStart)

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04647136
Acronym
FertStart
Enrollment
841
Registered
2020-11-30
Start date
2015-01-21
Completion date
2024-03-15
Last updated
2025-04-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Childbearing Intentions, Fertility Awareness

Keywords

Fertility awareness, Attitudes, Intentions, Fertility screening, Couples

Brief summary

Singapore, like many developed countries, is experiencing low birth rates, which is coupled with increasing age at first marriage and birth. In addition, demand for assisted reproduction technology treatments has increased over the years. Fertility awareness surveys have consistently shown that public awareness of age-related fertility decline and the limitations of fertility treatments is generally low, and this may lead to couples not optimising their fertility potential to achieve their family aspirations. This trial aims to study the effect of fertility health screening and fertility awareness tools on knowledge, attitudes and practice around childbearing among young Singaporean married couples.

Interventions

DIAGNOSTIC_TESTFertility Health Screening

Basic fertility health screening comprising an anti-Mullerian hormone (AMH) test and semen analysis, a doctor's consultation to explain the results, and standardised reproductive counselling by a trained nurse comprising a discussion of reproductive plans (including addressing barriers the couple face), education on age-related fertility decline and limitations of artificial reproductive technologies, advice on the optimal reproductive timing and when to seek further help. An educational brochure will be handed to the couple during the counselling session.

BEHAVIORALFertility Awareness Tools

Online intervention consisting of 1) video targeting fertility education and specific attitudes, social norms and perceived control for having children, 2) a fertility awareness tool (FERTISTAT) and 3) an educational brochure on fertility. This intervention can be self-administered and is therefore easily scalable.

Sponsors

KK Women's and Children's Hospital
CollaboratorOTHER_GOV
Singapore Health Services
CollaboratorOTHER
Duke-NUS Graduate Medical School
CollaboratorOTHER
Cardiff University
CollaboratorOTHER
National Population and Talent Division
CollaboratorUNKNOWN
Singapore General Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
25 Years to 34 Years
Healthy volunteers
Yes

Inclusion criteria

* Married couple * Both partners should be Singapore Citizens or Permanent Residents * Female partner is 25 - 34 years old at time of recruitment * Both partners agreeable and able to complete study procedures

Exclusion criteria

* Already have children, including from previous marriages * Pregnant * Currently undergoing or had previously went for any fertility evaluation and/or treatments * Self-reported history of previous ectopic pregnancy in the female partner * At least 1 partner unable to complete a self-administered questionnaire in English

Design outcomes

Primary

MeasureTime frameDescription
Change in parenthood intentionsBaseline (before intervention) and 6 months laterThe difference in the female partner's intended age at first birth at 6 months post-randomization compared to baseline, elicited by a direct question in pre and post-questionnaires.

Secondary

MeasureTime frameDescription
Change in fertility awarenessBaseline (before intervention) and 6 months laterThe difference in fertility awareness as measured by the Cardiff Fertility Knowledge Scale (CFKS) at 6 months post-randomization compared to baseline. The CFKS is a 13-item scale where each correct answer is assigned 1 point. Points are summed and converted to the % correct fertility knowledge score with a range of 0 - 100%.
Conception efforts6 moths post-randomizationProportion of couples who are (a) attempting to conceive, (b) pregnant, (c) who pursued more comprehensive fertility screening and/or (d) who pursued fertility treatment.
Birth number2 and 3 years post-randomizationNumber of births
Birth timing2 and 3 years post-randomizationTime to first birth

Countries

Singapore

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 13, 2026