Immunity
Conditions
Keywords
Garlic, Onion, Immunity
Brief summary
To analyze the efficacy of daily consumption of a combination of garlic and onion extracts on the incidence of respiratory infection symptoms in healthy elderly volunteers living in a residence. The duration of symptoms and related medication will also be studied.
Detailed description
It is a controlled, randomized, double-blind, parallel-group nutritional intervention study. 66 healthy elderly volunteers living in a nursing home will be randomly distributed into 2 equal groups: control group and intervention group. For 36 weeks the volunteers will take the product immediately after lunch. During that time they will maintain their lifestyle and nutritional habits. Every 4 weeks, the medical team of the residence will review the cases of respiratory diseases of infectious origin of the volunteers.
Interventions
DIETARY_SUPPLEMENTGarlic and onion concentrate
Garlic extract concentrate (equivalent to 2 garlic cloves) and onion extract concentrate (equivalent to 1 onion).
DIETARY_SUPPLEMENTControl
Microcrystalline cellulose
Sponsors
DOMCA S.A.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Masking description
Each volunteer is assigned a participant number that will be associated with a pot that will have all the product for the study. The pot number is the same as the participant number. The pot does not indicate which product it is carrying.
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Live in a nursing home with medical services. * Accept being vaccinated for the flu. * Freely accepted to participate in the study and sign the informed consent document. * Have the consent of the family.
Exclusion criteria
* Having any disease that affects the development and results of the study. * Be unable to understand the study and sign voluntarily and freely the informed consent. * Have a low expectation of compliance with the study protocol.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of respiratory symptoms associated with infections. | 36 weeks. | It will be reviewed if the volunteer has had any symptoms related to respiratory diseases of infectious origin. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Duration of symptoms. | 36 weeks | If the volunteer has had any symptoms related to respiratory diseases of infectious origin, every 4 weeks duration of these symptoms will be reviewed. |
| Consumption of medicines. | 36 weeks | If the volunteer has had any symptoms related to respiratory diseases of infectious origin, every 4 weeks treatment applied will be reviewed. |
Countries
Spain
Outcome results
None listed