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The Relationship Between Covid-19 Infection in Pediatric Patients and Secondary Lymphoid Organs

The Relationship Between Mild Covid-19 Infection in Pediatric Patients and Protection of Secondary Lymphoid Organs

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04646525
Enrollment
300
Registered
2020-11-30
Start date
2020-10-01
Completion date
2021-02-01
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adenoid Hypertrophy, Adenoiditis, Covid19, Immune Deficiency, Tonsil Hypertrophy, Tonsillitis

Keywords

pediatric, covid19, İmmune system

Brief summary

We aimed to find out whether the tonsils and nasal tissues of pediatric patients are the main factors that protects the children's immune system against COVID-19 infection.

Detailed description

Since it is known that the tonsil and adenoid tissues that are known as a secondary lymphoid organ, which form the first line of defense, are more active in childhood than adults, especially in the childhood age group, and since it has been scientifically shown that patients diagnosed with COVID-19 infection in the pediatric age group overcome this disease lightly than adults, we aimed to reveal whether the defined tonsil and adenoid tissues are the main factors that protect the children's immune system against COVID-19 infection.

Interventions

DIAGNOSTIC_TESTPhysical examination

Pediatric patients diagnosed with COVID-19 and who have had infection will be examined, adenoid and tonsillar tissues will be evaluated in terms of hypertrophy, chronic, or recurrent infection.

Sponsors

Selcuk University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
1 Years to 16 Years
Healthy volunteers
No

Inclusion criteria

* Patients with COVID-19 infection. * Patients aged between 1-16 years * Patients whose PCR test becomes negative

Exclusion criteria

* Patients with lymphoid tissue malignant disease * Patients with known lung disease * Patients with known systemic disease

Design outcomes

Primary

MeasureTime frameDescription
The primary outcome of our study was the evaluation of pediatric patients diagnosed with COVID-19 and who had COVID-19 infection in terms of adenoid and tonsillar tissue hypertrophy and the presence of chronic or recurrent infection.2020-2021The structure of the tonsil and adenoid tissues will be examined by physical examination, and the presence of tonsil and adenoid hypertrophy, tonsillitis, and adenoiditis conditions will be identified. The severity of covid-19 will be determined according to the cases of patients with tonsil and adenoid tissue disorders, who are hospitalized in intensive care, have infiltration in the lungs, and receive oxygen support.

Countries

Turkey (Türkiye)

Contacts

Primary ContactSelcen Celik
etikselcuk@gmail.com+9033222443963

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026