Chronic Cerebellar Stroke, Healthy Individuals (Controls)
Conditions
Keywords
Stroke, Cerebellar Disorders, Cerebrovascular Disorders, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Vascular Diseases, Cardiovascular Diseases, Cerebellar Stroke, Cerebellar Hemorrhage, Cerebellar Infarction
Brief summary
To test capacity of chronic cerebellar stroke patients and healthy individuals to learn and retain a complex bimanual motor skill, trained on the neurorehabilitation robot REAplan® (bimanual version).
Detailed description
Over 3 consecutive days, healthy individuals and chronic cerebellar stroke patients (1) will be evaluated and (2) will train on the neurorehabilitation robot REAplan®. They will practice several tasks on the robot REAplan® (bimanual version), requiring either movements with the affected arm (unimanual tasks) or complex, coordinated movements with both arms (bimanual tasks). In addition, several classical clinical scales and tests will be used to evaluate overall motor-sensory-cognitive functions (clinical tests, questionnaires, ...). Hand/digits motor function will be also evaluated with the kinetic device DexTrain®.
Interventions
DEVICEBimanual motor skill learning with the REAplan® rehabilitation robot
REAplan® rehabilitation robot: training to perform complex, coordinated, bimanual movements
Sponsors
Fonds National de la Recherche Scientifique
Université Catholique de Louvain
Louvain Bionics, UCLouvain
University Hospital of Mont-Godinne
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
Evaluation of bimanual motor skill learning
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
STROKE PATIENTS: Inclusion Criteria: * having a chronic cerebellar stroke (\>6 months) * aged 18-90 years * with a demonstrated stroke (ischemic or hemorrhagic) lesion on brain imaging
Exclusion criteria
* difficulty in understanding or executing commands * drug/alcohol abuse * severe aphasia / cognitive deficits interfering with study * inability to voluntarily move the affected arm (i.e. complete paralysis of the arm) * multiple strokes / dementia / psychiatric condition HEALTHY INDIVIDUALS: Inclusion Criteria: * 18-90 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in bi-SAT | Change between day 1 to 3 | Bimanual Speed/Accuracy Trade-off measured by the REAplan robot bimanual Speed/Accuracy Trade-off: mathematical computation of the relationship bewteen speed and accuracy |
| Change in bi-CO | Change between day 1 to 3 | Bimanual Coordination factor measured by the REAplan robot bimanual Coordination factor : mathematical measure of the phase coherence between velocities of both arms |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| change in bi-Force | Change between day 1 to 3 | Bimanual forces : forces exerted in the wrong direction by each arm (Newtons) |
| bi-Force | Day 1 + day 3 | On bimanual REACHING (REAplan robot) bimanual forces : forces exerted in the wrong direction by each arm (Newtons) |
| bi-smoothness | Day 1+ day 3 | On bimanual REACHING (REAplan robot) Smoothness of movement : Spectral Arc Length (SPARC) |
| bi-error | Day 1 + day 3 | on bimanual REACHING (REAplan robot) Error in centimeters or degrees during bimanual reaching |
| Dextrain | Day 1 + day 3 | Kinetic device measuring the movements of each finger: error and co-activation (percentage) |
| bi-SAT | Day 1 + day 3 | On bimanual REACHING (REAplan robot) bimanual Speed/Accurady Trade-off: mathematical computation of the relationship |
| Modified International Cooperative Ataxia Rating Scale (MICARS) | Day 1 | Ataxia scale A high score describes strong ataxia and a low score describes weak ataxia |
| Fugl Meyer Upper extremity test | Day 2 | Tests impairments of the upper limb after stroke |
| Corsi block | Day 2 | Tests the visuo-spatial memory |
| Montreal Cognitive Assessment (MoCA) | Day 2 | Tests the short-term memory, visuospatial skills, executive functions, attention, concentration, working memory, language and orientation in time and space |
| Abilhand and activlim | Day 3 | Questionnaire about the bimanual hability during activities of the daily life |
| BBT | Day 1 + day 3 | Box & Blocks Test (timed transfert of blocks from one space to the other) |
| bi-CO | Day 1 + day 3 | On bimanual REACHING (REAplan robot) bimanual Coordination factor: mathematical measure of the phase coherence between velocities of both arms |
Countries
Belgium
Outcome results
None listed