Urodynamics of Suprasacral Spinal Cord Injury Patients

Urodynamic Findings in Patients With Complete and Incomplete Suprasacral Spinal Cord Injury at Different Stages After Injury

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04642170

Enrollment

101

Registered

2020-11-24

Start date

2016-01-01

Completion date

2019-12-20

Last updated

2020-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal Cord Injuries

Brief summary

The medical records of 215 patients with spinal cord injury(SCI) at the Department of Rehabilitation Medicine of the 2nd Affiliated Hospital of Wenzhou Medical University, Wenzhou, China were evaluated between January 1, 2016 and December 20, 2019. According to the inclusion criteria and exclusion criteria, 101 patients were included. The patients were dichotomized into two groups: complete SCI group and incomplete SCI group, based on the American Spinal Injury Association Guidelines Impairment Scale (AIS) .The investigators retrospectively collected records of urodynamic evaluations of this patients and then analyze the urodynamic parameters,including detrusor overactivity (DO), bladder compliance (BC), bladder-filling sensation, maximum cystometric capacity (MCC), detrusor external sphincter dyssynergia (DESD), maximum urinary flow rate (Qmax), detrusor pressure at a maximum urinary flow rate(PdetQmax).

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

were: 1. the period of the spinal shock has passed. 2. patients diagnosed with traumatic suprasacral SCI, based on AIS. 3. urodynamic investigations were performed by the same urologist. 4. patients with voiding dysfunction.

Exclusion criteria

The patient with voiding dysfunction before the injury were excluded.

Design outcomes

Primary

Measure	Time frame	Description
bladder compliance (BC)	0-365 days after injury	bladder compliance in ml/cmH2O,one of the urodynamic parameters
detrusor overactivity (DO)	0-365 days after injury	detrusor overactivity in milliliter,one of the urodynamic parameters
bladder-filling sensation	0-365 days after injury	bladder-filling sensation,one of the urodynamic parameters

Secondary

Measure	Time frame	Description
detrusor external sphincter dyssynergia (DESD)	0-365 days after injury	detrusor external sphincter dyssynergia,one of the urodynamic parameters
maximum cystometric capacity (MCC)	0-365 days after injury	maximum cystometric capacity in milliliter,one of the urodynamic parameters

Other

Measure	Time frame	Description
maximum urinary flow rate (Qmax)	0-365 days after injury	maximum urinary flow rate in milliliter/second,one of the urodynamic parameters
detrusor pressure at a maximum urinary flow rate(PdetQmax)	0-365 days after injury	detrusor pressure at a maximum urinary flow rate in cmH2O,one of the urodynamic parameters

Outcome results