Gastroesophageal Varices, Liver Cirrhosis, Portal Hypertension
Conditions
Keywords
Esophagogastroduodenoscopy, Endoscopic ruler, Varices size
Brief summary
The presence of varices is a serious complication of portal hypertension in liver disease. To prevent variceal haemorrhage, screening and surveillance aims to detect high-risk varices related to varices size and determine the need for primary prophylaxis. Varices size evaluated by endoscopists might not be perfect reference, influenced by experience and machine. Endoscopic ruler is a novel tool to measure the varices size under the endoscopy. The investigators aim to evaluate the bias of varices size between endoscopists and endoscopic ruler as the reference.
Interventions
DIAGNOSTIC_TESTEndoscopic ruler
Endoscopic ruler for varices in portal hypertension Product uses: measuring the diameter of the veins under the endoscopy for the assessment of the risk of variceal haemorrhage in patients with portal hypertension Black and white measuring rule is highly recognizable under the endoscopy The width of each cell is 1 mm, and the measuring range is 0-10 mm With smooth edge, safe and reliable
Sponsors
LanZhou University
Tianjin Second People's Hospital
The First Affiliated Hospital with Nanjing Medical University
People's Hospital of Ningxia Hui Autonomous Region
The Second Affiliated Hospital of Baotou Medical College
The Third Xiangya Hospital of Central South University
The Second Hospital of Hebei Medical University
The Affiliated Hospital Of Southwest Medical University
First Hospital of China Medical University
Hepatopancreatobiliary Surgery Institute of Gansu Province
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* age between 18 and 75 years * clinically evident or biopsy-confirmed cirrhosis * Varices diagnosed by endoscopy * written informed consent
Exclusion criteria
* red sign * Active upper gastrointestinal bleeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The intraclass correlation coefficient (ICC) of the varix size and the kappa value of the varices bleeding risk between endoscopists and endoscopic ruler | 2020/11/13-2022/11/13 |
Secondary
| Measure | Time frame |
|---|---|
| The ICC value of the varix size and the kappa value of the varices bleeding risk among endoscopists | 2020/11/13-2022/11/13 |
| The bleeding rate of endoscopic ruler | 2020/11/13-2022/11/13 |
| The timing of endoscopic ruler | 2020/11/13-2022/11/13 |
| The correlation coefficient between varices size and hepatic venous pressure gradient | 2020/11/13-2022/11/13 |
| The correlation coefficient between varices size and decompensated events | 2020/11/13-2022/11/13 |
Countries
China
Contacts
Primary ContactXiaolong Qi, M.D.
Backup ContactYifei Huang, M.D.
Outcome results
None listed