Hysteroscopy Assisted Suction Curettage for Early Pregnancy Loss

Hysteroscopy Assisted Suction Curettage for Early Pregnancy Loss: Does it Reduce Retained Products of Conception and Postoperative Intrauterine Adhesions?

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04637373

Enrollment

Registered

2020-11-19

Start date

2019-07-01

Completion date

2020-12-31

Last updated

2020-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intrauterine Adhesion, Retained Products of Conception

Keywords

intrauterine adhesions, Hysteroscopy, Retained Products of Conception

Brief summary

Retained products of conception (RPOC) and intrauterine adhesions (IUA) may occur following suction curettage for early miscarriage and cause secondary infertility, recurrent pregnancy loss and pregnancy complications. The aim of this study is to investigate whether adding hysteroscopy to suction curettage reduces the rates of RPOC and IUA.

Detailed description

This is a descriptive, prospective study. Women aged 18-40 years admitted for surgical evacuation in cases of early missed abortion in a single university affiliated medical center are being recruited. All procedures performed under general anesthesia following cervical ripening with vaginal Misoprostol. Before the evacuation, a diagnostic hysteroscopy was performed to identify the pregnancy's implantation wall. Subsequently, ultrasound guided suction and curettage directed to the implantation wall is done. Finally, the uterine cavity is evaluated by hysteroscopy for RPOC. Participants are scheduled for follow-up diagnostic office hysteroscopy 2 months after termination of pregnancy for assessment of IUA and RPOC. However, due to restrictions on elective surgical procedures brought on by the Covid-19 pandemic, the follow-up hysteroscopy examination was postponed until 5 to 6 months after termination of pregnancy.

Interventions

DIAGNOSTIC_TESTHysteroscopy

adding Hysteroscopy before and after suction curettage for early missed abortion to define the wall of implantation and look for retained products of conception

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

PREVENTION

Masking

NONE

Intervention model description

This prospective descriptive study is taking place in a single university affiliated medical center.

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Women aged 18-40 years who were admitted to the gynecology emergency department at our institution with early miscarriage up to 12 weeks and 6 days of gestation, and choose surgical evacuation over medical treatment

Exclusion criteria

* incomplete and complete abortions, gestational age\>13 weeks of gestation, suspected molar pregnancy and patients' contraindications for general anesthesia.

Design outcomes

Primary

Measure	Time frame
the occurrence of Retained products of conception following suction curettage.	at the end of suction curettage procedure

Secondary

Measure	Time frame
the occurrence of intra uterine adhesions following targeted suction curettage	on follow-up office hysteroscopy, 5-6 months after the primary procedure

Countries

Israel

Contacts

Primary ContactOmer Moore, M.D

omer.moore@gmail.com+972505191242

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026