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Effect of Meibomian Gland Related Therapy on the Morphology of Meibomian Gland

Effect of Meibomian Gland Related Therapy on the Morphology of Meibomian Gland

Status
Withdrawn
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04636372
Enrollment
0
Registered
2020-11-19
Start date
2020-09-01
Completion date
2021-01-31
Last updated
2020-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Xerophthalmia

Brief summary

200 participants at Eye Hospital of Wenzhou Medical University during September, 2020 to November, 2020 will be enrolled in this study. The meibomian gland related therapy are pulsed light therapy and meibomian gland hot compress massage.

Interventions

Patients with xerophthalmia were treated with intense pulsed light of meibomian gland.

OTHERHot compress massage

Patients with xerophthalmia were treated with hot compress massage of meibomian gland.

Sponsors

Yune Zhao
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

* Previously untreated patients with xerophthalmia

Exclusion criteria

* No history of ocular surgery and trauma * Any eye diseases except xerophthalmia * No treated for xerophthalmia before * Successful completion of follow-ups

Design outcomes

Primary

MeasureTime frameDescription
The length of meibomian glands after the treatment.up to 2 monthsLength in millimeters.
The area of meibomian glands after the treatment.up to 2 monthsArea in millimeters\^2.
The percentage of meibomian glands after the treatment.up to 2 monthsPercentage of meibomian glands in %(area of meibomian glands (mm\^2) and area of palpebral conjunctiva (mm\^2) will be combined to report percentage of meibomian glands in %) are used to assess this outcome measure.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026