Metabolic Syndrome
Conditions
Brief summary
The growing prevalence of metabolic syndrome (MetS) in the worldwide is becoming a serious health problem and economic burden. MetS has become a crucial risk factor for the development of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD). The rising rates of CVD and diabetes, which are the two leading causes of death. To prevent the progression of MetS to diabetes and CVD, regular physical activity is required. Elliptical trainer device is a relatively new modality of exercise and is advertised to be superior to a treadmill because of the low joint impact and the more reasonable costs of an elliptical trainer compared to a treadmill. Additional quantitative research is needed to further evaluate the effectiveness of elliptical trainers and the physiological and perceptual responses to the machine.
Detailed description
Forty sedentary MeTS patients (from both sexes) will be randomly divided to group A and group B. -Group A (Elliptical training group): This group (n=20) will receive aerobic training on an elliptical trainer for 16 weeks (3 sessions per week). The session will start with 5 minutes warming up at 50 % of maximal heart rate (MHR), 20-minute continuous ET at 70% of MHR, 12 minutes (4×3) intervals at 90% of MHR with a 3-minute active recovery at 70% of MHR between intervals, and finally 5-minute cool-down period at 50% of MHR. Group B: this group will continue their normal daily physical activities without any additional training
Interventions
BEHAVIORALexercise training on elliptical device
This group (n=30) will receive aerobic training on an elliptical trainer for 16 weeks (3 sessions per week). The session will start with 5 minutes warming up at 50 % of maximal heart rate (MHR), 20-minute continuous ET at 70% of MHR, 12 minutes (4×3) intervals at 90% of MHR with a 3-minute active recovery at 70% of MHR between intervals, and finally 5-minute cool-down period at 50% of MHR
BEHAVIORALgroup B (control group)
this group will receive general advises on maintaining physical activities for 16 weeks without any additional supervised training
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
30 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* The MeTS subjects who will have three or more of the following criteria: 1) waist circumference more than 102 cm, triglycerides more than 150 mg/dL, 3) blood pressure (BP) more than 130/85 mmHg, 4) high-density lipoprotein (HDL) less than 40 mg/dL, .
Exclusion criteria
* Renal, pulmonary, cardiac, vascular, respiratory, hepatic, autoimmune disorders. * Smoker, addictive, cancer, and alcoholic patients. * Lower limb arthritis or any orthopaedic problem will hinder the training. * Participation in any type of sport training in the previous 6 months. * Pregnant or lactating women. * Patients with thyroid gland dysfunction.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Triglycerides | It will be measured after 16 weeks of training | Triglycerides is one of lipid profile indicators |
| high density lipoprotein | It will be measured after 16 weeks of training | high density lipoprotein is one of lipid profile indicators |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Fasting blood glucose | It will be measured after 16 weeks of training | It will be measured via a blood glucose meter |
| Insulin | It will be measured after 16 weeks of training | it will be measured via a blood sample |
| The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance | It will be measured after 16 weeks of training | HOMA-IR = \[fasting insulin (μU/mL) × fasting glucose (mmol)\]/22.5 |
| Systolic blood pressure | It will be measured after 16 weeks of training | It will be measured via Sphygmomanometer |
| weight | It will be measured after 16 weeks of training | the weight scale will be used |
| Leg strength test | It will be measured after 16 weeks of training | will be assessd by leg dynamometer |
| % body fat | It will be measured after 16 weeks of training | percentage of body fat composition |
| Waist circumference | It will be measured after 16 weeks of training | it will be measured by inelastic tape at the umbilicus level |
| diastolic blood pressure | It will be measured after 16 weeks of training | It will be measured via Sphygmomanometer |
Countries
Egypt
Contacts
Primary ContactAli Ismail, lecturer
Outcome results
None listed