Meibomian Gland Dysfunction
Conditions
Brief summary
To compare the effect of IPL combined with lipiflow and IPL combined with meibomian gland massage in treating meibomian gland dysfunction of different degrees ,focusing on effective rate, lasting time and changes of meibomian gland function and morphology.
Detailed description
To divide all participants into two groups, group one treated with IPL combined with Lipiflow and group two treated with IPL combined with meibomian gland massage.The following parameters were recorded after treatment: the effective rate, lasting time and changes of meibomian gland function and morphology.All parameters were compared between the two groups.
Interventions
PROCEDUREIPL/Lipiflow
To treat patients with MGD using intense pulsed light combined with lipiflow
PROCEDUREIPL/MGX
To treat patients with MGD using intense pulsed light combined with meibomian gland massage
Sponsors
Aier School of Ophthalmology, Central South University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* patients with meibomian gland dysfunction * patients with ocular discomfort * skin type:FitzpatricⅠ-Ⅳ
Exclusion criteria
* patients with acute ocular inflammation * eye surgery history in the last 12 months * patients who have received IPL or Lipiflow in the last 12 months * patients who wear contact lens in last one month
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| ocular surface disease index(OSDI) | 6 months | The OSDI is assessed on a scale of 0 to 100,with higher scores representing greater disability |
| meibomian gland expressibility score and meibum quality score | 6 months | The score is on a scale of 0 to 6.The higher scores, the severity of the meibomian gland function(the highest score is 6 and the lowest score is 0) |
| meibomian gland dropout score | 6 months | the higher scores, the severity of the meibomian gland morphology(The highest score is 6 and the lowest score is 0) |
| Breakup time | 6 months | the shorter time, the poorer of the tear film stability |
Contacts
Primary ContactYan Chen, doctor
Outcome results
None listed